jQuery match first letter in a string and wrap with span tag

I'm trying to get the first *letter* in a paragraph and wrap it with a `` tag. Notice I said letter and not character, as I'm dealing with messy markup that often has blank spaces. **Existing markup** (which I can't edit):

Actual text starts after a few blank spaces.

**Desired result:**

Actual text starts after a few blank spaces.

How do I ignore anything but `/[a-zA-Z]/` ? Any help would be greatly appreciated.
What should happen in the case of the following html:

15346 Actual text starts after a few blank spaces, and numbers.

, should the A still be wrapped, or should there be no wrapping?

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